I’d like to recommend Jenny Pox by J.L. Bryan. A few reasons why:
1. Girl who spreads plague by touch in small-town South Carolina. You had me at the premise. You had me at the location.
2. Jenny doesn’t ever get whiny even though her lot is a miserable one. In fact, she’s pretty darned active. She has hobbies, she does stuff to get what she wants, she’s not really afraid of playground tyrants.
3. As a lot of reviews I found mentioned, the world comes alive. Some people found the main antagonist Ashleigh to be too much, but I found myself loving to hate her.